The Effect of Adding Indirect Relationship to Turbo Similarity Searching

نویسندگان

  • Nurul H. A. Hassain Malim
  • Yong Pei-Chia
  • Marwah H. Al-Laila
  • Shereena M. Arif
چکیده

Received: June 05, 2015 Revised: May 09, 2016 Accepted: May 11, 2016 Abstract: Background: Turbo Similarity Searching (TSS) has been proved as one of the effective and simple searching method in Cheminformatics. Emerging from the conventional similarity searching, TSS depended on the concept of fusion where relationship between the target being sought and the compound in the database are indirect. Previous works has looked at only one level of indirect relationship and indicates that there are further potential that more levels of such relationship be added to TSS to increase its ability to recover more actives. Hence, in this work, we aimed to investigate the impact of the indirect relationship on TSS.

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تاریخ انتشار 2016